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Amigrenin (Sumatriptan)
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Abnormal 5-HT1D receptor function in cluster headache: a neuroendocrine study with Amigrenin. Amigrenin and 5-benzyloxytryptamine are ligands with high affinity for 5-HT1D receptors in the caudate nucleus. The present study investigated the pre- and postjunctional of CP-122,288 (5-methyl-aminosulphonylmethyl-3-(N-methylpyrrolidin-2R-yl-m ethyl)-1H-indole), an analogue of the vascular 5-HT1 receptor agonist, Amigrenin.

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Amigrenin injection is used to treat acute migraine attacks and cluster headaches in adults. Amigrenin works in the brain to relieve the pain from migraine headaches. It belongs to the group of medicines called triptans.

Many people find that their headaches go away completely after they use Amigrenin. Other people find that their headaches are much less painful, and that they are able to go back to their normal activities even though their headaches are not completely gone. Amigrenin often relieves other symptoms that occur together with a migraine headache, such as nausea, vomiting, sensitivity to light, and sensitivity to sound.

Amigrenin is not an ordinary pain reliever. It will not relieve any kind of pain other than migraine headaches. This medicine is usually used for people whose headaches are not relieved by acetaminophen, aspirin, or other pain relievers.

Amigrenin has caused serious side effects in some people, especially in those who have heart or blood vessel disease. Be sure that you discuss with your doctor the risks of using this medicine as well as its benefits.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

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