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Comenter (Selegiline)

These findings indicate possible therapeutic differences between PFS and Comenter in the treatment of neurodegenerative disorders. Pharmacokinetic aspects of l-deprenyl (Comenter) and its metabolites. Comenter pretreatment protected SCG neurons and their postganglionic nerve fibers in SMG against these changes in a dose-dependent manner.

Other names for this medication:
Selegiline, Eldepryl, Anipryl, Carbex, Comenter, Deprenyl, Jumex, Niar, Segan, Selecom, Selegilina, Selegos, Selerin, Selgene, Selgian, Selgin, Selgina, Zelapar,

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This medication is used to treat movement disorders caused by Parkinson's disease. It does not cure Parkinson's disease, but it may improve shakiness (tremor), muscle stiffness, loss of normal movement as your dose of other Parkinson's medication wears off (end-of-dose failure), and sudden switching between normal movement and stiffness ("on-off" problems). It may improve your range of motion and ability to walk, dress, and exercise. Comenter is usually used in combination with other medicines (e. g. , levodopa, carbidopa). Comenter is an enzyme blocker (MAO inhibitor) that works by slowing the breakdown of certain natural substances in the brain (neurotransmitters such as dopamine, norepinephrine, and serotonin).

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Ischemia resulted in a significant reduction of high-energy phosphate compounds and an accumulation of nucleotide degradation products, particularly adenosine, in the myocardium. Survival differences were examined for four periods, i.e., 1960-1964, 1965-69, 1970-74, and 1975-79. These were naked-eye clinical examination alone, clinical examination with the aid of total-body photographs, epiluminescence microscopy (ELM), digital ELM, computer-assisted techniques, and teledermatology. The influence of social stress on time perception and psychophysiological reactivity. The structured physical examination to detect defects in the pubovisceral portion of the levator ani muscle can be learned as shown by good interrater agreement.

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In general, cirrhosis mortality rates were positively associated with alcohol consumption and negatively associated with AA membership. However, agonists, quipazine and trifluoromethylphenylpiperazine, with greater reported affinities for 5HT binding sites on rat brain membranes than MK212 were without effect as were the antagonists metergoline, methysergide, cyproheptadine, mianserine and methiothepin. Characterizing cardiac metabolism in heart failure (HF) revealed several metabolic alterations called metabolic remodeling, ranging from changes in substrate use to mitochondrial dysfunction, ultimately resulting in ATP deficiency and impaired contractility. Detection of antibody-carrying bacteria in patients with pyelonephritis The study was strictly designed with randomization, double-blinding, and placebo-controlled method to observe the efficacy and immune memory 11 years following hepatitis B vaccination.

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The most important conclusion is that at the lowest temperature studied, where the effect of carbon surface composition on adsorption properties is the most strongly marked, the value of paracetamol maximal adsorption decreases as the amount of surface basic groups and carbonyls increases. We have focused attention on mammalian enamel formation because it relies on a self-assembling protein complex to direct mineral habit.

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The different trees yielded roughly similar topologies, but varied in the number of steps and branch support. No general or local adverse effects were noted in the patients studied. In conclusion, these data strongly suggest that GnRH neurons are directly sensitive to insulin and implicate for the first time the MAPK Erk1/2 signaling pathway in the central effects of insulin on the neuroendocrine reproductive axis. Our treatment protocol for the neurogenic bladder is therefore dependent on identifying those children who have very short or nonexistent safe periods.

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High tacrolimus blood concentrations early after lung transplantation and the risk of kidney injury. Exponential synchronization of generalized neural networks with mixed time-varying delays and reaction-diffusion terms via aperiodically intermittent control. Pelvic floor muscle training has long been the most common form of conservative treatment for stress urinary incontinence. Preoperative atrial fibrillation and long-term survival after open heart surgery in a rural tertiary heart institute. The search was complemented with bibliography searching of the reference list of the trials retrieved from the electronic search.

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Is secondary hyperparathyroidism an important etiologic factor in the anemia of chronic renal failure? Despite intensive support efforts, the patient died 1 day after the sudden change. Recognition of complex sound signals of different duration in a successive complex

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In vitro inhibitory effects of non-steroidal anti-inflammatory drugs on 4-methylumbelliferone glucuronidation in recombinant human UDP-glucuronosyltransferase 1A9--potent inhibition by niflumic acid. The data sets are simultaneously fit using a least-squares criterion, and both models are found to accurately reproduce the experimental results.

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Principles for Health System Capacity Planning: Insights for Healthcare Leaders. Using metabolic labeling, phosphoamino acid analysis, and mutagenesis studies, we found that arrestin-3 is constitutively phosphorylated at Thr-382 and becomes dephosphorylated upon beta(2)-adrenergic receptor activation in COS-1 cells. Regression analyses were used to identify clinicopathological and imaging variables associated with relapse-free survival (RFS) and overall survival (OS). Rates of 12-month psychotropic medication use are stratified by respondent socio-demographic characteristics, and the distribution of 12-month DSM-IV CIDI disorders is estimated among past-12-month use of antidepressants and stimulants.

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Formulation of pDNA vaccines in Vaxfectin may improve their potency in human clinical trials. These conditions may facilitate the diffusion of chemotherapeutic agents to the interior of a tumor. Role of recombinant human granulocyte-macrophage colony stimulating factor for large scale collection of peripheral blood stem cells for autologous transplantation. This study compared the location and gene and protein expression of secreted phosphoprotein 1 in placental and uterine tissues supplying a normally sized and the smallest fetus carried by hyperprolific Large White and Meishan gilts on Days 41-42 of pregnancy.

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This action would then give rise to the synchronous and cyclical activity in the ganglia and contribute to the characteristic peripheral neuropathy. HDL apolipoprotein-mediated lipid efflux involves multiple cellular proteins to remove both cholesterol and phospholipids that are otherwise stored in the cells. These findings may be relevant to the induction of mucosal tolerance.

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Ascorbic acid injections prior to pilocarpine suppressed behavioral seizure episodes by increasing the latency to the first myoclonic, clonic and tonic seizure and decreasing the percentage of incidence of clonic and tonic seizures as well as the mortality rate. We evaluated minipigs as a potential alternative to NHPs to test the safety of this class of compounds. During primary angioplasty, abciximab enhances myocardial reperfusion, translating into a reduced incidence of 6-month left ventricular remodeling. In 2012, the first national consensus statement on oral health care during pregnancy was issued, emphasizing both the importance and safety of routine dental care for pregnant women.

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Recent studies indicate that tendon progenitors exhibit stem cell-like properties, i.e., differentiation to osteoblasts, adipocytes, and chondrocytes, in addition to tenocytes. Here we review current knowledge on modifications of CSN and CRL components including CSN subunits, SRSs and cullins causing tumorigenesis with emphasis on urological neoplasia. In addition to a standard monolayer culture technique, cells were maintained in suspension. Management of postoperative pain: review of current techniques and methods.

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Since AOS is usually detected on films obtained to screen children with Down syndrome for AAS, the atlanto-occipital joint should be carefully studied on these radiographs. The implications of this for radiotherapy are that simple formulas are unlikely to be accurate predictors of acute effects in altered fractionation schemes. This is followed by an increase in p27(Kip1) protein expression due to enhanced protein stability.

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Distribution of metallothionein in normal and pathological human skin. p73, a structural and functional homolog of p53, plays an important role in modulating cell cycle arrest. (2) Lack of correlation between physiological availability of beta-glucuronidase and the high levels measured by the standard assay. Such increased lobbying should occur on behalf of, and in collaboration with, service users, and accordingly the authors describe a range of activities under the broad headings of pro-active and reactive lobbying. Evaluation of subclinical laminitis in a dairy herd and observations on associated nutritional and management factors.

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A greater index of suspicion is needed to timely treat aero-digestive foreign bodies in children with neurological impairment. Antisera raised against the expressed product of clone TB1 recognized a 55-kDa protein in M. Neer Award 2016: reduced muscle degeneration and decreased fatty infiltration after rotator cuff tear in a poly(ADP-ribose) polymerase 1 (PARP-1) knock-out mouse model. Since GP-3 is resident on the inner surface of the zymogen granule membrane, it should appear on the outer cellular surface after exocytosis. We determined whether flaxseed lignan causes clinical hypoglycemia or hypotension in healthy older adults as an important aspect of safety.

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Ureteral quintuplication with renal atrophy in an infant after the 1986 Chernobyl nuclear disaster. This indicated that defect in the S-RNase expression was not the sole reason for the loss of self-incompatibility in tomato.

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Spatial summation in relation to the dynamics of warmth sensation. For patients with ovarian metastases from gastric cancer, surgical resection in addition to chemotherapy might be an effective treatment. Comment on ion transit pathways and gating in ClC chloride channels. Similarly, regular consumption of mesalazine, a drug structurally related to NSAIDs, seems to reduce the risk of CRC in patients with ulcerative colitis. We recently showed that handling of a chromium-containing disc resulted in chromium deposition on the skin.

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This study uses national survey data and takes into account the heterogeneity of SSRI and TCA users so the results can be generalized to real clinical practice. The American Pharmacists Association facilitated this process by convening a broad working group of members and other involved parties to draft a preliminary definition. In bronchoalveolar lavage fluid, total and differential cell counts were determined. However, these methods may utilize different basis set and electron-ion potential representations. IGF-1R/epithelial-to-mesenchymal transition (EMT) crosstalk suppresses the erlotinib-sensitizing effect of EGFR exon 19 deletion mutations.

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Further work is needed to clarify how schools can provide WASH services daily. These spectral differences are attributed to marked changes in the degrees of electron delocalisation for the two types of radical, both rings of the indole being involved for the 6H5MI radical but only the benzenoid moiety for the 5H6MI radical.

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Macrophage migration inhibitory factor (MIF) inhibits macrophage migration and has pleiotropic activities on immune and inflammatory responses, cell growth, and glucose metabolism. Costs and financial feasibility of long-term drug therapy of chronic polyarthritis Insights into the subsurface transport of As(V) and Se(VI) in produced water from hydraulic fracturing using soil samples from Qingshankou Formation, Songliao Basin, China. LC-HF rats were more sensitive to melanotan-II and less sensitive to SHU9119. Endocrine and behavioural plasticity in response to juvenile stress in the semi-precocial rodent Octodon degus.

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In vivo detection of scrapie cases from blood by infrared spectroscopy. Traditional educational means, for example professional journals, were appreciated because of their flexible use in terms of time and location. It is suggested that brainstem dopamine D(2) receptors mediate suppression of consummatory ingestive behavior and that D(2) receptors in the shell region of the nucleus accumbens mediate the display of gapes and chin rubs, but that neither of these D(2) receptor populations mediate the hedonic evaluation of taste.

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The significance and robustness of our approach are demonstrated on a variety of experiments. Mentalizing Family Violence Part 2: Techniques and Interventions.

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Data from the first wave of the Survey on Health, Ageing and Retirement (SHARE) on formal (nursing care and paid domestic help) and informal care (support provided by relatives) are used to study the probability and the quantity of both types of care. An operative technique is described as a salvage treatment for severe subglottic and supraglottic laryngeal stenosis. Despite many studies of acquired prosopagnosia, there have been only a few attempts at its rehabilitation, all in single cases, with a variety of mnemonic or perceptual approaches, and of variable efficacy. Finally, we highlight some limitations of the BLAST algorithm as currently implemented and suggest possible improvements for barcoding applications.

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The scopolamine (0.8 mg/kg)-induced EEG amplitude increase reversing potency of a subthreshold dose of the muscarinic agonist pilocarpine (2 mg/kg) was not potentiated by ondansetron, methysergide or alaproclate. Polyomavirus (Py) DNA replication is regulated by its enhancer, which contains an AP1 site, c-Jun and c-Fos, the products of nuclear protooncogenes c-jun and c-fos, form the heterodimeric transcriptional activating factor AP1. An extensive and diverse set of molecular overlays for the validation of pharmacophore programs. However, hydrophobicity analysis of the deduced amino acid sequence of the 70-kD protein had strongly suggested that this might also be a membrane protein. The acclimatization to extreme environments and its physiological mechanisms

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Adherence to yoga and its resultant effects on blood glucose in Type 2 diabetes: A community-based follow-up study. This region encodes an ORF (ORF154) whose gene product was found to be homologous to a family of phosphotransferases. The fear of falling can be attenuated by providing interventions to reduce the impact of modifiable risk factors that were identified in this study.

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Latina mothers, particularly those with mental health problems, improve after PHN FHV services. The public health and economic consequences of Plasmodium falciparum malaria are once again regarded as priorities for global development.

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The aim of this study was to elucidate the structure of a potential ageing marker for Cava sparkling wine. It is essential to develop new vaccination strategies and prophylactic antiviral medications. Lithium pretreatment of rats did not affect seizure activity induced by administration of N-methyl-D-aspartate, kainic acid, bicuculline, or pentylenetetrazole. Review of available trials of selective decontamination of the digestive tract (SDD).

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To assess whether tubal ligation and hysterectomy affect subsequent risk of ovarian cancer. Because in zone electrophoresis conductivity in a zone always changes more or less, the additivity of variances is never perfectly valid. Upon irradiation of the azide complexes of the chromium(III) protoporphyrin-IX reconstituted myoglobin and cytochrome c peroxidase with ultraviolet light aerobically at room temperature, the characteristic optical and EPR spectra for nitridochromium(V) derivatives were observed. The primary role of cardiac rate in adapting cardiac output to changing physiological needs has been more clearly recognized in recent years. MMC is an independent factor associated with the need for positive pressure ventilation and intubation at birth.

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Methodological considerations for future research are discussed. Furthermore, 20 alpha-HSD activity in the cytosol fraction from malignant tumours was increased dramatically by passage through the DEAE column, suggesting that the enzyme is present in the cytosol as an inactive or sequestered form. Clear evidence indicates an inverse linear dose response between amount of physical activity and all-cause mortality, total CV disease, and CAD incidence and mortality. Asthma and anti-asthmatic medications have been suggested as risk factors for increased susceptibility to caries. Gastrointestinal stromal tumors (GISTs), 10-year experience: patterns of failure and prognostic factors for survival of 127 patients.

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Adenovirus terminal protein mediates both nuclear matrix association and efficient transcription of adenovirus DNA. Curcumin inhibited MNU-induced photoreceptor cell apoptosis by suppressing DNA oxidative stress. A quantitative analysis of experimental data for posttranslational translocation into the endoplasmic reticulum is performed. Rorschach assessment of traumatized refugees: an exploratory factor analysis. Steroid hormone abnormalities in women with severe idiopathic constipation.

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All of the mice injected with nonpurged cell mixtures developed leukemia and died, whereas the mice transplanted with ZnPcS2P2-PDT-treated mixtures had a longer survival time, and the fewer leukemic cells there were in the cell mixtures, the higher the leukemia-free survival rate. Barriers to racemization in C3-symmetric complexes containing the hydrotris(2-mercapto-1-ethylimidazolyl)borate (Tm(Et)) ligand. Psychophysical thresholds were obtained using a modified method of limits. Electrophysiological and vegetative indicators of human emotional response to dynamic color music Like other South Asians, Bangladeshis are unduly prone to develop CAD, which is often premature in onset, follows a rapidly progressive course and angiographically more severe.

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Although a questionnaire response showed that many Swedes are concerned about oral galvanism, it seems that the symptoms changed as each theory was challenged. Moreover, stricter limit values could prevent chronic occupational damage to the respiratory system. Early termination of pregnancy, or menstrual regulation, is recommended for use within 7 weeks of amenorrhea, ie 49 days. amikacin and ampicillin for treatment of neonatal bacterial infections.

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Interestingly, PCs did not show a significant correlation with spatial coordinates. We find that TDG interacts in vitro and in vivo with the p160 coactivator SRC1, with the interaction being mediated by a previously undescribed motif encoding four equally spaced tyrosine residues in TDG, each tyrosine being separated by three amino acids.

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Rapid high performance liquid chromatographic assay for determination of voriconazole concentration in human plasma. The value of validated vulnerability data for conservation planning in rapidly changing landscapes. The College of Nursing, State University of New York Health Science Center at Brooklyn, operates a nursing center in conjunction with a nonprofit social work agency.

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Neurological and sphingteral impairments were present mainly in our elderly patients. In further investigations on this protein preparation (called factor C) we are able to show an additional influence on the tumour-cytolytic activities of mononuclear cells. Dimethicone/antacid but not alginate/antacid, produced a significant improvement in oesophagitis, oesophageal ulceration and histological grade of inflammation over the 8-week treatment period so that 14 patients treated with dimethicone/antacid and 10 with alginate/antacid had normal endoscopic oesophageal appearances at the end of the study.

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Females born of these rats (F1) exhibited glucose intolerance and impaired insulin secretion in vivo at adulthood. The capillary basal membrane of kidney in diabetic rats is thicker and the ground substance is increased. Electron microscopy demonstrated that adult isolated hepatocytes survived and proliferated in the rat spleen for more than 16 mo, retaining the structural elements of hepatic cytoplasm while reconfiguring a hepatic sinusoidal architecture. 1,25(OH)2D3 treatment down-regulated several genetic pathways related to neuroangiogenesis, cellular motility, and invasion, including pathways for axonal guidance, Rho GDP signaling, and matrix metalloprotease inhibition.

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Fis is a small, basic, site-specific DNA-binding protein present in Escherichia coli. For the theta band it increased from baseline values during tasks solution in men, while in women it decreased during the analytic task. A comparative study of skin tolerance after using oestradiol patch and gel in Thai postmenopausal women. We observe complete suppression of the excitation laser and multiphoton emissions.

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Since uremic toxins in the middle molecule range have been postulated to be responsible for erythropoiesis suppression in end-stage renal disease, and in addition, insufficient erythropoietin production and the clearance of some middle molecular weight substances is six times greater with CAPD than with hemodialysis, it appears that CAPD can normalize the hematocrit in patients with end-stage renal disease who were anemic on other modalities with little or no change in serum creatinine, provided the remnant kidneys are capable of producing sufficient erythropoietin. A 40-year-old woman underwent operative hysteroscopy for suspected submucosal myoma, during which the uterine fundus was perforated. Dopamine D2 receptors attenuate phosphatidylinositol 4,5-bisphosphate in synaptosomal membranes from rat neostriatum. For example, the capacity of ochratoxin A to inhibit natural killer cell activity and increase growth of transplantable tumour cells has been associated with renal and hepatic carcinomas in mice and might similarly contribute to human cancer. Test compounds used in this study were augmentin pill pictures selected on their ability to cause a calcium increase in cultured lenses.

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Surveillance generic names for enalapril data alone have played major roles in immunization strategy changes. The modified inner cylinder showed higher potential for enhanced mixing of gelatinized starch and the enzyme than the conventional cylinder. Like SERP, the 130-kDa protein exhibits a region homologous to cysteine proteinases, suggesting that these proteins, or their processing products, may play a role as proteinases at the time of merozoite release from the infected erythrocyte. Microheterogeneity and species-related differences among myelin basic proteins.

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Isolation and identification of constituents from Cudrania javanensis. From 2010, all hospitalised suspected malaria cases at the malaria clinic of the Regional Medical Research Centre for Tribals in Bastar district, central laroxyl 10 mg drake right hand India, were screened.

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Murine tumor cell line (S-EL4) sensitivity to TNF cytotoxicity is augmented when cycloheximide is added together with TNF or when cycloheximide is added 1 hr before or after TNF. Targeted oligonucleotide-mediated microsatellite identification (TOMMI) from large-insert library clones. The instrument also importantly allows for an assessment of the impact of chronic and long-term conditions on medication usage and hindered access to education. In this report we show that IL-18BPa, the IL-18BP isoform with the highest affinity for IL-18, was strongly induced by IL-12 in human PBMC. This cell death platform then activates monsignor vincenzo tizanidine hcl procaspases in the intrinsic cell death pathway.

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The clinical evaluation of cobalamin deficiency by determination of methylmalonic acid in serum or urine is not invalidated by the presence of heterozygous methylmalonic-acidaemia. Before describing the various treatments of these ulcers, the author discusses their etiological process. The amino acid sequence of losartan cipla brand name the products of the desA genes revealed the presence of four conserved domains.

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Altered left ventricular diastolic properties during pacing-induced ischemia in dogs with coronary stenoses. Mechanisms by which these interactions nasal spray fluconazole may result in observed motile phenomena are proposed. We tested 72 Mandarin-English bilingual college students with a range of language-dominance profiles in the 2 languages and ages of acquisition of English.

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No commercially available phantoms are designed specifically for whole-body scanning of infants. Proteomic analysis of epithelioma papulosum cyprini cells ribavirin side effects without interferon side infected with spring viremia of carp virus. Using standardized patients in advanced practice nursing education.