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Prilactone (Spironolactone)
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Spironolactone

Prilactone is a potassium-sparing diuretic that was approved many years ago. Until recently, it was used primarily to treat edema resulting from liver cirrhosis, primary hyperaldosteronism and nephrotic syndrome. It has been used in combination with potassium-wasting diuretics to prevent hypokalemia. Recent research on this older diuretic has focused on its effect in patients with left-sided congestive heart failure (CHF). As an aldosterone-blocking agent, Prilactone is postulated to work synergistically with angiotensin-converting enzyme (ACE) inhibitors to provide more thorough blockade of the renin-angiotensin-aldosterone (RAA) system.

Other names for this medication:
Spironolactone, Aldactone, Aldactazide, Aldactazine, Aldazida, Aldazide, Aldozone, Alexan, Alizar, Carpiaton, Espirone, Espironolactona, Expal, Kespirona, Lanx, Letonal, Osiren, Osyrol, Practon, Prilactone, Spiractin, Spiresis, Spirix, Spiroctan, Spirolang, Spirolon, Spiron, Spirono, Spironolacton, Spironolactona, Spironolakton, Spironolattone, Spirotone, Verospiron, Xenalon,

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Prilactone comes as a tablet and suspension (liquid; Carospir) to take by mouth. It usually is taken once or twice a day. Take Prilactone suspension consistently either with food or without food each time. Take Prilactone at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Prilactone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the oral suspension well before each use to mix the medication evenly.

Your doctor may start you on a low dose of Prilactone and gradually increase your dose.

Prilactone tablets and suspension release the medication differently in your body and cannot be substituted for one another. Only take the Prilactone product prescribed by your doctor and do not switch to a different Prilactone product unless your doctor says that you should.

Prilactone controls high blood pressure, edema, heart failure, and hyperaldosteronism but does not cure these conditions. It may take about 2 weeks or longer before the full effect of Prilactone occurs. Continue to take Prilactone even if you feel well. Do not stop taking Prilactone without talking to your doctor.

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Effect of subinhibitory concentrations of antimicrobial agents on adherence to silicone and hydrophobicity of coagulase-negative staphylococci. In contrast, T3 treatment had no effect on the acetylation of histones and the recruitment of corepressors and coactivators at the T3RU that mediates the T3 activation of acetyl-CoA carboxylase-alpha gene transcription. Evaluation of the Learning Curve for Transurethral Plasmakinetic Enucleation and Resection of Prostate Using a Mentor-based Approach. Understanding the genetic basis of human longevity remains a challenge but could lead to life-extending interventions and better treatments for age-related diseases. Nitrous oxide formation in the Colne estuary, England: the central role of nitrite.

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Factors associated with treatment outcome in 64 HIV negative patients with multidrug resistant tuberculosis. The acid dissociation constant (pKa) is among the most frequently used physicochemical parameters, and its determination is of interest to a wide range of research fields. Niosomes play an increasingly important role in drug delivery as they can reduce toxicity and modify pharmacokinetic and bio-availability. At the same time, The study discussed a method to get the quantitative similarity values of different producing areas samples. Evolution of codon usage in the smallest photosynthetic eukaryotes and their giant viruses.

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